YMC*Gel Amino

primary amine (-NH2) functionality stable, high coverage monomeric bonded chemistry for aqueous normal phase separations of saccharide type compounds in place of silica for conventional NP chromatography using non-polar solvents for HILIC separations of highly polar compounds

General

YMC*Gel Amino is specifically used for the analysis of mono- and polysaccharides under aqueous normal phase elution conditions. It can also be used in place of silica for conventional normal phase chromatography using non-polar solvents and for HILIC separations of highly polar compounds.

Properties

YMC*Gel Amino is based on a monomeric bonding of a primary propylamine functionality to YMC’s spherical, ultra pure, high surface area silica with a mean pore diameter of 12 nm. The amine functionality provides retention and allows the separation of polar compounds under aqueous normal phase or HILIC elution conditions, e.g. the analysis of mono- and polysaccharides using acetonitrile/water eluents. Since YMC*Gel Amino operates under normal phase elution conditions, water, which is more polar than acetonitrile, is the stronger solvent.

YMC*Gel Amino can also be used for the separation of isomers of tocopherols and other organic soluble compounds such as paraffins, olefins and aromatics under conventional normal phase conditions.

In aqueous, low pH buffers the amino phase becomes a weak anion exchanger capable of separating
negatively charged molecules.