- fully endcapped, monomeric phenyl phase
- unique selectivity due to pi - pi interactions
- preferential retention of aromatic compounds
- alternative selectivity to L18 or C4 bonded
phases
for the analysis of peptides and other
biomolecules
|
|
 |
| YMC*Gel Phenyl |
Specification |
| Pore size / nm |
12 |
30 |
| Particle size / µm |
3; 5; 15 |
5 |
| Surface area / m2g-1 |
330 |
100 |
| Carbon content / % |
9 |
3 |
| Recommended pH range |
2.0 - 7.5 |
2.0 - 7.5 |
Note: Analytical grades (3 µm and 5 µm) are not available as bulk materials; they are only available in prepacked columns. |
General
YMC*Gel Phenyl is a high density bonded phase (9 % carbon load on 12 nm silica) and is fully
endcapped. This results in a superior bonded phase with proven performance and exceptional lifetime
for a phenyl reversed phase material.
Properties
YMC*Gel Phenyl provides a unique selectivity when compared to aliphatic straight chain reversed
phases such as C18, C8 or C4. The pi-electrons of the phenyl groups can interact with aromatic
residues of an analyte molecule in addition to hydrophobic interactions to increase retention relative
to non-aromatic species.
Phenyl phases are convenient for the separation of aromatic compounds and also provide a useful
alternative to C18 or C4 phases for the separation of peptides and proteins on both small pore (12
nm) and wide pore (30 nm) materials. Retention is decreased on wide pore phenyl phases relative to
12 nm phenyl material due to the lower surface area of the wide pore material. |
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